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Up for sale "Interplanetary Travels" Gottfried Schatz Hand Signed Announcement Dated 1991.
1 October 2015) was a Swiss-Austrian biochemist. chatz was born in Strem. Upon
obtaining his PhD in chemistry and biochemistry at the University of Graz (Austria), he did postdoctoral work at the University of Vienna and at "The Public Health
Institute" of the City of New York. In 1968, he emigrated to the US in
order to assume a professorship Cornell University in Ithaca, New York. Six years later, he returned to Europe in order to
join the newly created Biozentrum at the University of Basel,
which he chaired from 1983 to 1985, From 1984 to 1989 he was Secretary General
of the European Molecular Biology Organization (EMBO). After his
retirement in 2000, he presided the Swiss Science and Technology
Council (SSTC) until 2003. He is the author of more than 200
professional publications as well as of two books of essays on the broader
implications of science. His scientific was
published in 2000. Schatz died on 1 October 2015, aged 79. Schatz played a
leading role in elucidating the biogenesis of mitochondria and in discovering mitochondrial DNA. He recognized that this DNA encoded
only a small number of mitochondrial proteins which was decisive for his
further research on the import of proteins into the mitochondria and the
degradation of proteins within these organelles. Schatz discovered a complex
transport system that recognizes mitochondrial proteins made in the cytoplasm
by specific signals attached to these proteins and then transfers them into the
mitochondria. This system comprises two protein complexes, TOM and TIM, which are localized in the outer and inner
mitochondrial membranes respectively. Mutations in these complexes can disrupt
protein import and cause illnesses such as the neurodegenerative Mohr-Tranebjaerg syndrome,
which leads to deafness. Schatz also demonstrated that the energy-requiring
protease Lon regulates protein turnover within the mitochondria, thus
maintaining the integrity and the proper functioning of mitochondrial DNA.
Gottfried Schatz is the author of more than 200 scientific publications, three
volumes of essays, an autobiography and a
novel. His books have appeared in English, French, Greek and Czech translation.